The Aedes aegypti cell line Aag2 was derived by Peleg in 1975 and adapted in 1991 by Lan and Fallon. It was selected for sequencing based of its susceptible to infection by many arboviruses including: Dengue, Chikungunya, Zika, Sindbis, Rift Valley Fever Virus, amongst others and the ability to perform molecular biology in the cell line. Genome sequencing was performed on genomic DNA purified from cells acquired from Andrea Gamarnik's lab at the FundaciĆ³n Instituto Leloir . The passage number is unknown, but considering the date of its derivation, it most likely a highly passaged cell line. A full analysis of the Aag2 cell line genome is made in the article The Diversity, Structure, and Function of Heritable Adaptive Immunity Sequences in the Aedes aegypti Genome (Whitfield Z.J, Dolan P.T. et al, Current Biology, 2017). The Aag2 cell line is also persistently infected with Cell Fusing Agent Virus (an insect specific Flavivirus), and the insect-specific bunyavirus Phasi Charoen-like virus (PCLV) Maringer et al. BMC Genomics 2017 .
Aedes aegypti

Aedes aegypti exists in at least two forms (considered either subspecies or separate species according to different authors), namely A. aegypti formosus (the original wild type found in Africa) and A. aegypti aegypti (the worldwide urban form). The yellow fever mosquito, Aedes aegypti aegypti, has a worldwide distribution in the tropics and subtropics where it is the main vector of both dengue and yellow fever viruses. It can also transmit chikungunya and Zika viruses.

Genome assemblies and gene sets